Article

Biomolecular condensates undergo a generic shear-mediated liquid-to-solid transition

2020-01-28

Abstract excerpt

A wide range of systems containing proteins have been shown to undergo liquid-liquid phase separation (LLPS) forming membraneless compartments, such as processing bodies 1 , germ granules 2 , stress granules 3 and Cajal bodies 4 . The condensates resulting from this phase transition control essential cell functions, including mRNA regulation, cytoplasm structuring, cell signalling and embryogenesis 1–4 . RNA-...

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Literature Corpus work: 8700154a-620f-5709-8aeb-3e1f2764a6ba
DOI: 10.1101/2020.01.21.912857

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