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Differences in pathogenetic mechanism between Tibetan and Han high-altitude polycythemia based on a whole genome-wide association study

2023-08-09

Abstract excerpt

High-altitude polycythemia (HAPC) is a common and serious chronic disease affecting people of highland and plains ancestry living at high altitudes. This study investigated genetic susceptibility differences for HAPC among ethnic groups, with 2,248 volunteers participating, including 898 HAPC patients (n Han = 450, n Tibetan = 448). The study included a GWAS of 198 cases (n Han = 100, n Tibetan = 98), which reveal...

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Literature Corpus work
86fef747-06d9-51d8-9d47-395834b99d74
DOI
10.1101/2023.08.05.23293524
Open publication

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