Article
Associations of high-altitude polycythemia with polymorphisms in PIK3CD and COL4A3 in Tibetan populations.
Human genomics - 27 Jul 2018
Fan Xiaowei, Ma Lifeng, Zhang Zhiying, Li Yi, Hao Meng, Zhao Zhipeng, Zhao Yiduo, Liu Fang, Liu Lijun, Luo Xingguang, Cai Peng, Li Yansong, Kang Longli
Abstract excerpt
BACKGROUND: High-altitude polycythemia (HAPC) is a chronic high-altitude disease that can lead to an increase in the production of red blood cells in the people who live in the plateau, a hypoxia environment, for a long time. The most frequent symptoms of HAPC include headache, dizziness, breathlessness, sleep disorders, and dilation of veins. Although chronic hypoxia is the main cause of HAPC, the fundamental...
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