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Article

CYP17A1 and CYP2E1 variants associated with high altitude polycythemia in Tibetans at the Qinghai-Tibetan Plateau.

Gene - 25 Jul 2015

Xu Jin, Yang Ying-zhong, Tang Feng, Ga Qin, Wuren Tana, Wang Zhan, Ma Lan, Rondina Matthew T, Ge Ri-li

Abstract excerpt

Tibetans adapt to high altitude environments through low blood hemoglobin concentrations. Previous work has identified that CYP17A1 and CYP2E1 genes exhibit evidence of local positive selection for this Tibetan high-altitude adaptation. Nevertheless, despite this apparent genetic advantage, some...

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PMID: 25917616
DOI: 10.1016/j.gene.2015.04.056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25917616-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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