Article

In vivo mapping of striatal neurodegeneration in Huntington’s disease with Soma and Neurite Density Imaging

2025-03-17

Abstract excerpt

<h4>Background</h4> Huntington’s Disease (HD) is an inherited neurodegenerative disorder characterised by progressive cognitive and motor decline due to atrophy in basal ganglia networks. No disease-modifying therapies exist, but novel clinical trials are ongoing. Non-invasive imaging biomarkers sensitive to HD neuropathology are essential for evaluating therapeutic effects. Soma and Neurite Density Imaging (SAND...

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Literature Corpus work: 86e69633-044c-5c88-bf4f-1c6f948eff6f
DOI: 10.1101/2025.03.17.25324107

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