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Automated Histological Assessment of Parkinson’s Disease Models via Integrated Dopaminergic Neuron Segmentation and Phenotypic Quantification

2026-07-15

Abstract excerpt

<title>Abstract</title> <p>Accurate quantification of dopaminergic neurons and their phenotypic state is essential for understanding neurodegeneration and evaluating therapeutic efficacy in Parkinson’s disease models. Traditional approaches, such as stereological counting, are labor-intensive and limited to structural assessment, while most automated methods neglect key biochemical markers like Tyrosine Hydroxyla...

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Literature Corpus work
edf3f98a-690a-5cec-8565-902c2cf61409
DOI
10.21203/rs.3.rs-10278708/v1
Open publication

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Automated Histological Assessment of Parkinson’s Disease Models via Integrated Dopaminergic Neuron Segmentation and Phenotypic QuantificationDOI 10.21203/rs.3.rs-10278708/v1
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