Article

Molecule guided laser ablation as a novel therapeutic strategy to control itch

2017-11-27

Abstract excerpt

Itch is a major symptom of many chronic skin diseases that can exacerbate inflammation by provoking excessive scratching and causing skin damage. Here we develop a novel technology to control itch through molecular guided delivery of a phototoxic agent and near infrared (IR) illumination of the skin. Exploiting the selective binding of the pruritogen Interleukin-31 to itch sensing cells, we generate an engineered...

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Literature Corpus work: 86bfbfd9-d82a-516e-b009-56eb09963b29
DOI: 10.1101/225391

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