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Article

Age-associated epigenetic changes in mammalian sperm: implications for offspring health and development

24 Aug 2022

Abstract excerpt

BACKGROUND: Modern reproductive behavior in most developed countries is characterized by delayed parenthood. Older gametes are generally less fertile, accumulating and compounding the effects of varied environmental exposures that are modified by lifestyle factors. Clinicians are primarily concerned with advanced maternal age, while the influence of paternal age on fertility, early development and offspring...

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Share to Epigenetics and DNA Methylation
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PMID: 36066418
DOI: 10.1093/humupd/dmac033

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