Article

Transcriptome-Driven Constraint-Based Modelling Reveals Metabolic Targets for Ovarian Cancer

2025-06-24

Abstract excerpt

<h4>ABSTRACT</h4> Constraint-based modelling (CBM) is a powerful computational approach that reconstructs cellular metabolism by integrating ‘omics data with genome-scale metabolic models (GEMs), enabling in silico hypothesis generation and genetic engineering studies. Advances in high-throughput ‘omics technologies and the complete mapping of the human genome have expanded the application of CBM to human system...

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Literature Corpus work: 86846bde-76d1-5061-9b99-c65975d6933a
DOI: 10.1101/2025.06.24.661329

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