Article

INTEGRATE: Model-based multi-omics data integration to characterize multi-level metabolic regulation

2021-08-13

Abstract excerpt

Metabolism is directly and indirectly fine-tuned by a complex web of interacting regulatory mechanisms that fall into two major classes. First, metabolic regulation controls metabolic fluxes (i.e., the rate of individual metabolic reactions) through the interactions of metabolites (substrates, cofactors, allosteric modulators) with the responsible enzyme. A second regulatory layer sets the maximal theoretical leve...

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Literature Corpus work: b6acaf28-3cfe-5b37-89e0-71d119eed157
DOI: 10.1101/2021.08.13.456220

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