Article

Mosaic Regulation of Stress Pathways Underlies Senescent Cell Heterogeneity

2024-10-04

Abstract excerpt

Cellular senescence (CS) and quiescence (CQ) are stress responses characterised by persistent and reversible cell cycle arrest, respectively. These phenotypes are heterogeneous, dependent on the cell type arrested and the insult inciting arrest. Because a universal biomarker for CS has yet to be identified, combinations of senescence-associated biomarkers linked to various biological stress responses including lys...

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Literature Corpus work: 865b48d9-3099-534b-8128-3b6d62849f32
DOI: 10.1101/2024.10.03.616489

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