Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Towards a context-aware framework for cellular senescence.

Biogerontology - 6 May 2026

Nath Arnab, Mehrotra Parul, Bhattacharyya Chiranjib, Saini Deepak Kumar

Abstract excerpt

From a cellular perspective, senescence has been considered a binary state, wherein cells are either senescent or not. This reductionist notion, often defined as irreversible growth arrest, has guided efforts to identify universal biomarkers and senolytics, but both have consistently eluded us. This outcome is not surprising, given that the biological nature of senescence may not be strictly irreversible; the...

Topics

Cellular Senescence
Humans
Animals
Biomarkers
Aging
Phenotype

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 42089944
DOI: 10.1007/s10522-026-10440-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Towards a context-aware framework for cellular senescence.PMID 42089944Read ↗

Cellular senescence: Neither irreversible nor reversibleSemantic proximity Read ↗

A guide to assessing cellular senescence in vitro and in vivoSemantic proximity Read ↗

Cellular Senescence: Mechanisms and Therapeutic PotentialSemantic proximity Read ↗

Impact of Senescent Cell Subtypes on Tissue Dysfunction and Repair: Importance and Research QuestionsSemantic proximity Read ↗

Senescence under appraisal: hopes and challenges revisitedSemantic proximity Read ↗

Hallmarks of cellular senescence: biology, mechanisms, regulationsSemantic proximity Read ↗

Understanding cellular senescence: pathways involved, therapeutics and longevity aidingSemantic proximity Read ↗

Hallmarks of Cellular Senescence.Semantic proximity Read ↗

Cellular senescence in ageing: from mechanisms to therapeutic opportunities.Semantic proximity Read ↗

Hallmarks and mechanisms of cellular senescence in aging and diseaseSemantic proximity Read ↗

Emerging insights in senescence: pathways from preclinical models to therapeutic innovationsSemantic proximity Read ↗

Senescence: An Identity Crisis Originating from Deep Within the Nucleus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.