Article

Cytoplasmic FMR1-interacting protein 2 regulates cocaine reward by modulating synaptic plasticity in the nucleus accumbens

2022-10-24

Abstract excerpt

<title>Abstract</title> <p>Cytoplasmic FMR1-interacting protein 2 (CYFIP2), consisting of the Wiskott–Aldrich syndrome protein family verprolin-homologous protein (WAVE) regulatory complex, is involved in actin polymerization, contributing to neuronal development and synaptic plasticity. Mutating serine-968 to phenylalanine (S968F) in CYFIP2 causes an altered cocaine response in mice; however, the neuronal mechan...

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Literature Corpus work: 85f89697-00d2-5d99-a9fc-5987ea235ecf
DOI: 10.21203/rs.3.rs-2111114/v1

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