Article

Pirenperone relieves the symptoms of fragile X syndrome in Fmr1 knockout mice

2022-08-11

Abstract excerpt

<title>Abstract</title> <p>Fragile X syndrome (FXS) is one of the neurodevelopmental disorders that is caused by loss of FMRP. Many challenges have not succeeded to develop the proper therapeutics. FMRP is an RNA binding protein which can bind and recognize different RNA structures and regulate the target mRNAs’ translation involved in neuronal synaptic plasticity. Perturbations of this gene expression network ha...

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Literature Corpus work: dd69b8e8-f702-58bc-8975-e03551b1074e
DOI: 10.21203/rs.3.rs-1936948/v1

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