Article

Multi-Species Phenotypic Screening across Disease Models of Mucolipidosis Type IV

2021-03-05

Abstract excerpt

Invertebrate model organisms (the nematode Caenorhabditis elegans and the fruit fly Drosophila melanogaster ) are valuable tools to bridge the gap between traditional in vitro discovery and preclinical animal models. Invertebrate model organisms are poised to serve as better disease models than 2D cellular monocultures for drug discovery, as well as easier and more cost-effective to scale up than 3D organoids/as...

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Literature Corpus work: 85945f11-3197-52ee-b132-66e10bca446e
DOI: 10.1101/2021.03.05.434120

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