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Article

The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types.

Proceedings of the National Academy of Sciences of the United States of America - 2 Apr 2002

Hersh Bradley M, Hartwieg Erika, Horvitz H Robert

Abstract excerpt

The misregulation of programmed cell death, or apoptosis, contributes to the pathogenesis of many diseases. We used Nomarski microscopy to screen for mutants containing refractile cell corpses in a C. elegans strain in which all programmed cell death is blocked and such corpses are absent. We iso...

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Identifiers

PMID: 11904372
DOI: 10.1073/pnas.062065399
PMCID: PMC123652

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11904372-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types.PMID 11904372Read ↗

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