Article

<i>In vivo</i> quantitative high-throughput screening for drug discovery and comparative toxicology

2022-08-28

Abstract excerpt

Quantitative high-throughput screening (qHTS) evaluates the pharmacology of drug and investigational agent libraries for potential therapeutic uses, toxicological risk assessment, and increasingly for academic chemical tool discovery. Phenotypic HTS assays aim to interrogate molecular pathways and networks, often relying on cell culture systems, historically with less emphasis on multicellular organisms. C. elega...

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Literature Corpus work: 014b6606-8436-5761-8274-26fec2b8b3c5
DOI: 10.1101/2022.08.26.505462

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