Article
DNA methylation modulates allograft survival and acute rejection after renal transplantation by regulating the mTOR pathway
2020-07-06
Abstract excerpt
Acute rejection (AR) can lead to allograft dysfunction following renal transplantation, despite immunosuppressive treatments. Accumulating evidence points out a role for epigenetic modification in immune responses. However, the mechanism and contribution of DNA methylation in allograft survival remain unclear. In this study, we followed up patients who successively experienced end-stage renal disease, renal transp...
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Identifiers and source
- Literature Corpus work
- 85776cef-d58a-5e6d-88c2-e6b4f70bce65
- DOI
- 10.1111/ajt.16183