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Article

Genetics and Epigenetics of Chronic Allograft Dysfunction in Kidney Transplants.

Iranian journal of kidney diseases - 1 Jan 2016

Zununi Vahed Sepideh, Samadi Nasser, Mostafidi Elmira, Ardalan Mohammad Reza, Omidi Yadollah

Abstract excerpt

Chronic allograft dysfunction is the most common cause of allograft lost. Chronic allograft dysfunction happens as a result of complex interactions at the molecular and cellular levels. Genetic and environmental factors both influence the evolution and progression of the chronic allograft dysfunction. Epigenetic modification could be considered as a therapeutically modifiable element to pause the fibrosis process...

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PMID: 26837673

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