Article
Epigenetics in Kidney Transplantation: Current Evidence, Predictions, and Future Research Directions.
Transplantation - 1 Jan 2016
Mas Valeria R, Le Thu H, Maluf Daniel G
Abstract excerpt
Epigenetic modifications are changes to the genome that occur without any alteration in DNA sequence. These changes include cytosine methylation of DNA at cytosine-phosphate diester-guanine dinucleotides, histone modifications, microRNA interactions, and chromatin remodeling complexes. Epigenetic modifications may exert their effect independently or complementary to genetic variants and have the potential to...
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