Article

Systematic identification of conditionally folded intrinsically disordered regions by AlphaFold2

2022-02-18

Abstract excerpt

The AlphaFold Protein Structure Database contains predicted structures for millions of proteins. For the majority of human proteins that contain intrinsically disordered regions (IDRs), which do not adopt a stable structure, it is generally assumed these regions have low AlphaFold2 confidence scores that reflect low-confidence structural predictions. Here, we show that AlphaFold2 assigns confident structures to ne...

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Literature Corpus work: 856c908e-b347-5a57-80f9-a9c8d9dd8e29
DOI: 10.1101/2022.02.18.481080

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