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Dietary fiber supplementation increases Drosophila melanogaster lifespan and gut microbiota diversity

1 Jan 2024

Abstract excerpt

genes in the gut of older flies, possibly delaying the gut dysbiosis connected to the age-related gut immune dysfunction. Brain proteome analysis showed that DFS led to the modulation of metabolic processes connected to mitochondrial biogenesis, the RhoV-GTPase cycle, organelle biogenesis and maintenance, membrane trafficking and vesicle-mediated transport, possibly orchestrated through a gut-brain axis...

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PMID: 38912918
DOI: 10.1039/d4fo00879k

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