Article

Lapatinib protects against epileptic seizures via halting glutathione peroxidase 4-dependent ferroptosis

2020-05-30

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background and Purpose</h4> Repetitive epileptic seizures trigger massive neuronal death. Therefore, neuroprotection plays a role in preventing neuronal death and inversely suppresses seizure generation. Additionally, some studies have shown ferroptosis, featured by lipid peroxidation (a dominant form of oxidative stress in the brain), is of paramount importance in epileptic seizures. Lapat...

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Literature Corpus work: 8528954b-1b1f-51c1-8c92-484a5d42cc3f
DOI: 10.1101/2020.05.28.120733

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