Article

Temozolomide (TMZ) Inhibits Glioma Cell Proliferation by Inducing Ferroptosis: Effect and Mechanism

2026-05-27

Abstract excerpt

<title>Abstract</title> <p>Background Although temozolomide (TMZ) is a first-line chemotherapeutic agent for treating malignant gliomas, its mechanism of action remains to be incompletely understood, and elucidating the molecular mechanisms underlying TMZ's mode of action is crucial for improving its therapeutic efficacy. Methods This study aimed to delineate the effects of TMZ on glioma cells and the molecular...

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Literature Corpus work: 25e49c4e-de29-55b1-8a58-b4226da9961e
DOI: 10.21203/rs.3.rs-9740279/v1

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