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GLS2 reduces the occurrence of epilepsy by affecting mitophagy function in mouse hippocampal neurons

1 Oct 2024

Abstract excerpt

BACKGROUND: Altered mitophagy has been observed in various neurological disorders, such as epilepsy. The role of mitophagy in causing neuronal damage during epileptic episodes is significant, and recent research has indicated that GLS2 plays a crucial role in regulating autophagy. However, exactly how GLS2 affects epilepsy is still unclear. AIMS: To investigate the expression and distribution characteristics of...

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PMID: 39404053
DOI: 10.1111/cns.70036

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