Article

Investigation into the Effect and Mechanism of Temozolomide (TMZ) Inducing Ferroptosis to Inhibit Glioma Cell Proliferation

2024-06-28

Abstract excerpt

<title>Abstract</title> <p>Although temozolomide (TMZ) is a first-line chemotherapeutic agent for treating malignant gliomas, its mechanisms of action remain incompletely understood, and primary or acquired resistance is prevalent in certain patients, severely limiting its clinical efficacy. Therefore, elucidating the molecular mechanisms underlying TMZ's mode of action is crucial for improving its therapeutic ef...

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Literature Corpus work: 6d84db0e-ea4f-5572-aa8c-b5b5dae00cbc
DOI: 10.21203/rs.3.rs-4560862/v1

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