Article
Diethylstilbestrol exposure in utero: A paradigm for mechanisms leading to adult disease
1 Jan 2005
Abstract excerpt
The synthetic estrogen diethylstilbestrol (DES) was administered to pregnant women between the 1940s and the mid-1970s and is believed to be responsible for numerous uterine/cervical/vaginal malformations and cancers that appeared after birth and in young adult life. This medical tragedy has served as one of the prototypical examples of a phenomenon known as "endocrine disruption," in which either environmental...
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