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Article

Differential transcriptional invasion signatures from patient derived organoid models define a functional prognostic tool for head and neck cancer

2023-11-08

Abstract excerpt

<title>Abstract</title> <p>Clinical outcome for patients suffering from head and neck squamous cell carcinoma (HNSCC) remains poor. This is mostly due to highly invasive tumors that cause loco-regional relapses after initial therapeutic intervention. The molecular pathways governing the detrimental invasive growth modes in HNSCC remain however understudied. Here, we have established HNSCC patient derived organoid...

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Literature Corpus work
84a40d99-9c94-524e-9167-b1dd5d1da2b7
DOI
10.21203/rs.3.rs-3487002/v1
Open publication

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Differential transcriptional invasion signatures from patient derived organoid models define a functional prognostic tool for head and neck cancerDOI 10.21203/rs.3.rs-3487002/v1
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