Article
Phenotype remodelling of HNSCC cells in the muscle invasion environment.
Journal of translational medicine - 7 Oct 2024
Zeng Guozhong, Shen Yi, Sun Wei, Lu Huanzi, Liang Yujie, Wu Jiashun, Liao Guiqing
Abstract excerpt
BACKGROUND: Tumour invading muscle in head and neck squamous cell carcinoma (HNSCC) is often associated with destructive growth and poor prognosis. However, the phenotypic functions and pathological mechanisms of muscle-invasive cancer cells in tumour progress remains unknown. In this study, we aimed to investigate the phenotypic functions of muscle-invasive cancer cells of HNSCC and their potential crosstalk...
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