Article

Intra-pol proviral open region of HTLV-1 controls the transcription from both long terminal repeats

2025-06-09

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold> Human T-cell leukemia virus type 1 (HTLV-1) infects mainly CD4<sup>+</sup> T lymphocytes and causes two types of disease: the aggressive malignancy known as Adult T-cell leukemia/lymphoma (ATL) and a number of chronic inflammatory syndromes. HTLV-1 infection is established by integration of proviral DNA (~9000bp) into the host genome. In HTLV-1, two viral genes,...

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Literature Corpus work: 4e4a87fe-bb80-55c4-ae9c-58b370f7d871
DOI: 10.21203/rs.3.rs-6815109/v1

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