Article

Comprehensive Multi‐Omics Integration Reveals B Cell‐Derived ELL2 as a Novel Diagnostic and Prognostic Biomarker in Sepsis

2025-06-06

Abstract excerpt

We analyzed bulk transcriptome sequencing data from 10 cohorts of sepsis patients. Using unbiased patient clustering, we identified three subtypes with significantly different prognoses, which were consistently reproduced across all 10 cohorts. Through comprehensive multi-angle analyses, we revealed distinct differences among the subtypes in terms of inflammation, immune responses, and functional pathways. By inte...

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Literature Corpus work: 7a43c960-002a-57d8-ae58-4cd7c6c61009
DOI: 10.1002/mdr2.70010

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