Article

Towards a diagnostic test for sporadic ALS utilising deep learning and SNP microarrays

2025-04-15

Abstract excerpt

A variety of common and rare genetic factors have been implicated in the development of amyotrophic lateral sclerosis (ALS), and the evidence is that a genetic component is present in most affected individuals. However, our current understanding of ALS genetics causally explains only a small proportion of sporadic cases which represent over 90% of all people with ALS. This limits the utility of genetic testing in...

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Literature Corpus work: 84831369-6286-5968-9967-f26f7105c7b6
DOI: 10.1101/2025.04.12.25325716

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