Article

Non metastasis protein 2 (NME2) is a potential target for leukemia-specific immunotherapy

2022-07-25

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> NME2 is an immunogenic overexpressed tumor-associated antigen in chronic myeloid leukemia (CML). We evaluated NME2’s antigenicity in common HLA-backgrounds as a potential target for CML-specific immunotherapy. <bold>Methods:</bold> NME2-specific cytotoxic T-lymphocytes (CTL) were generated by stimulating cultured PBMCs with artificial antigen presenting cells (a...

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Literature Corpus work: 84787cda-d96d-5399-851a-a779ddf5630d
DOI: 10.21203/rs.3.rs-1855482/v1

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