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Bone marrow stromal cell antigen 2: Tumor biology, signaling pathway and therapeutic targeting (Review)

18 Jan 2024

Abstract excerpt

Bone marrow stromal cell antigen 2 (BST2) is a type II transmembrane protein that serves critical roles in antiretroviral defense in the innate immune response. In addition, it has been suggested that BST2 is highly expressed in various types of human cancer and high BST2 expression is related to different clinicopathological parameters in cancer. The molecular mechanism underlying BST2 as a potential tumor...

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PMID: 38240088
DOI: 10.3892/or.2024.8704

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