Article

The basolateral amygdala-anterior cingulate pathway contributes to depression and its comorbidity with chronic pain

2022-08-11

Abstract excerpt

While depression and chronic pain are frequently comorbid, underlying neuronal circuits, and their relevance for the understanding of psychopathology, remain poorly defined. Here we show in mice that hyperactivity of the neuronal pathway linking the basolateral amygdala to the anterior cingulate cortex is essential for chronic pain-induced depression. In naive animals, we demonstrate that activation of this pathwa...

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Identifiers and source

Literature Corpus work: 846849be-f41e-5d1f-83a6-399eb29467d1
DOI: 10.1101/2022.08.09.503276

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