Article

Spatially resolved cellular and circuit architecture of the insular cortex controlling different dimensions of pain

2026-07-20

Abstract excerpt

Chronic pain is a leading cause of human suffering, affecting about 20% of the population. The insular cortex (IC) is a central hub for the multidimensional experience of pain, yet how the diverse neurons in IC are organized and assembled into functional circuits remains unclear. Here, combining multiplexed error-robust fluorescence in situ hybridization (MERFISH), neural tracing and in vivo functional analyses, w...

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Literature Corpus work: b51745e3-fe19-54bb-93db-402ed9e90785
DOI: 10.64898/2026.07.15.738697

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