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Transcriptional and cellular signatures of cortical morphometric remodelling in chronic pain

23 Sept 2021

Abstract excerpt

ABSTRACT: Chronic pain is a highly debilitating and difficult to treat condition, which affects the structure of the brain. Although the development of chronic pain is moderately heritable, how disease-related alterations at the microscopic genetic architecture drive macroscopic brain abnormalities is currently largely unknown. Here, we examined alterations in morphometric similarity (MS) and applied an...

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PMID: 34561394
DOI: 10.1097/j.pain.0000000000002480

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