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Single-cell landscape of primary central nervous system diffuse large B-cell lymphoma

12 Jun 2023

Abstract excerpt

Understanding tumor heterogeneity and immune infiltrates within the tumor-immune microenvironment (TIME) is essential for the innovation of immunotherapies. Here, combining single-cell transcriptomics and chromatin accessibility sequencing, we profile the intratumor heterogeneity of malignant cells and immune properties of the TIME in primary central nervous system diffuse large B-cell lymphoma (PCNS DLBCL)...

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PMID: 37308475
DOI: 10.1038/s41421-023-00559-7

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