Article
Investigating the mechanisms controlling cell survival during the first steps of embryonic differentiation
2017-01-01
Abstract excerpt
In the mouse and human embryo the onset of differentiation is accompanied by a dramatic series of changes at the level of gene expression, epigenetics, signalling, and metabolism. During this period the epiblast becomes hypersensitive to death stimuli and defective cells are eliminated. Cell competition has been proposed as a quality control mechanism that compares cell fitness levels within a cell population and...
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Identifiers and source
- Literature Corpus work
- 8452deb5-8b9f-585c-b1a7-b03c00e1ea37
- DOI
- 10.25560/51501