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Article

Cell competition from development to neurodegeneration

30 Jun 2021

Abstract excerpt

Cell competition is a process by which suboptimal cells are eliminated to the benefit of cells with higher fitness. It is a surveillance mechanism that senses differences in the fitness status by several modes, such as expression of fitness fingerprints, survival factor uptake rate and resistance to mechanical stress. Fitness fingerprints-mediated cell competition recognizes isoforms of the transmembrane protein...

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PMID: 34190316
DOI: 10.1242/dmm.048926

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