Article
Mechanisms of cell competition emerging from Drosophila studies.
Current opinion in cell biology - 1 Oct 2017
Baker Nicholas E
Abstract excerpt
Cell competition was described in Drosophila as the loss from mosaic tissues of otherwise viable cells heterozygous for Ribosomal protein mutations ('Minutes'). Cell competition has now been described to occur between multiple other genotypes, such as cells differing in myc expression levels, or mutated for neoplastic tumor suppressors. Recent studies implicate innate immunity components, and possibly mechanical...
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