Article

Rational drug design targeting intrinsically disordered proteins

2023-08-26

Abstract excerpt

Abstract Intrinsically disordered proteins (IDPs) are proteins that perform important biological functions without well‐defined structures under physiological conditions. IDPs can form fuzzy complexes with other molecules, participate in the formation of membraneless organelles, and function as hubs in protein–protein interaction networks. The malfunction of IDPs causes major human diseases. However, drug design t...

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Literature Corpus work: 843adb11-ee17-56de-b53a-0b4f88e1abd4
DOI: 10.1002/wcms.1685

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