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Association of DEK Gene Alterations with Prognosis and Immunotherapy Treatment in Advanced Squamous Cell Carcinoma of the Lung

2025-10-27

Abstract excerpt

<title>Abstract</title> <p>Background: The DEK::AFF2 fusion has been recently described in sinonasal squamous cell carcinomas; however, its presence and clinical impact in pulmonary squamous cell carcinoma (SCC) remain unclear. This study aimed to investigate the frequency of DEK rearrangement and DEK::AFF2 fusion in advanced lung SCC and to evaluate their association with PD-L1 expression, prognosis, and respons...

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Literature Corpus work
840937a0-eeb6-5233-a8a8-fd1f7d6f8231
DOI
10.21203/rs.3.rs-7897885/v1
Open publication

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