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Article

Sinonasal Squamous Cell Carcinoma with DEK::AFF2 Rearrangement : An Aggressive Cancer with Bland Morphology.

The American journal of surgical pathology - 1 Nov 2024

Trinquet Aude, Laé Marick, Lépine Charles, Lanic Marie-Delphine, Lacheretz-Szablewski Vanessa, Shaar Chneker Caroline, Goujon Jean-Michel, Favier Valentin, Costes-Martineau Valérie

Abstract excerpt

AIMS: DEK::AFF2 squamous cell carcinoma is a recently described cancer entity, with 29 cases reported to date. Occasionally, these carcinomas appear deceptively indistinguishable; however, specific morphological and phenotypic features suggest the presence of this rearrangement. However, the prognostic value of this diagnosis remains unclear. We aimed to report a new case series with histological, molecular, and...

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Share to Carcinoma, Squamous Cell
Share to Chromosomal Proteins, Non-Histone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to In Situ Hybridization, Fluorescence

Share to Oncogene Proteins

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Share to Squamous Cell Carcinoma of Head and Neck

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Identifiers

PMID: 39132684
DOI: 10.1097/PAS.0000000000002281

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