Article
DEK-AFF2 Carcinoma of the Sinonasal Region and Skull Base: Detailed Clinicopathologic Characterization of a Distinctive Entity.
The American journal of surgical pathology - 1 Dec 2021
Rooper Lisa M, Agaimy Abbas, Dickson Brendan C, Dueber Julie C, Eberhart Charles G, Gagan Jeffrey, Hartmann Arndt, Khararjian Armen, London Nyall R, MacMillan Christina M, Palsgrove Doreen N, Nix J Stephen, Sandison Ann, Stoehr Robert, Truong Tra, Weinreb Ilan, Bishop Justin A
Abstract excerpt
A novel DEK-AFF2 fusion was recently reported in 4 nonkeratinizing squamous cell carcinomas of the sinonasal region and skull base, including 1 with exceptional response to immunotherapy, but it is not yet clear if this rearrangement defines a unique clinicopathologic category or represents a rare event. This study aims to characterize a larger cohort of carcinomas with DEK-AFF2 fusions to assess whether they...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.