Article

4 Short Hairpin RNA Lentiviral Vector-Based System for TRIM5α Knockdown in Cynomolgus Monkey Embryonic Fibroblast Cells Against HIV Infection

2022-02-22

Abstract excerpt

<h4>Background: </h4> The restriction factor, TRIM5α is known to limit retroviral infection at an early post-entry stage in a species-specific manner. The current study was designed to assess the efficacy of TRIM5α in restricting the human immunodeficiency virus (HIV) using a pseudo-viral infection model in cynomolgus monkey embryonic fibroblast cells (CMEFs down the TRIM5α expression using the lentivirus short ha...

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Literature Corpus work: 83951478-fb9a-5bdc-81f2-161632bb4e1d
DOI: 10.21203/rs.3.rs-1264721/v1

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