Article

Efficient production of salvianic acid A from L-dihydroxyphenylalanine through a tri-enzyme cascade

2023-02-15

Abstract excerpt

Salvianic acid A (SAA), used for treating cardiovascular and cerebrovascular diseases, possesses several pharmacological properties. However, the current methods for the enzymatic synthesis of SAA show low efficiency. Here, we constructed a three-enzyme cascade pathway in Escherichia coli BL21(DE3) to produce SAA from L-dihydroxyphenylalanine (L-DOPA). The phenylpyruvate reductase ( La PPR) from Lactobacillus sp....

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Literature Corpus work: 8393ee2b-9dee-583a-9b3c-aec53271e080
DOI: 10.21203/rs.3.rs-2562087/v1

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