Back to search

Article

Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumours

2017-07-27

Abstract excerpt

The implementation of personalised medicine in childhood cancers has been limited by a lack of clinically validated multi-target sequencing approaches specific for paediatric solid tumours. In order to support innovative clinical trials in high-risk patients with unmet need, we have developed a clinically relevant targeted sequencing panel spanning 311 kb and comprising 78 genes involved in childhood cancers. A to...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
835b4a56-ab9d-54fc-a0fb-9fd3a0b347b3
DOI
10.1101/165746
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Development of a targeted sequencing approach to identify prognostic, predictive and diagnostic markers in paediatric solid tumoursDOI 10.1101/165746
Select a neighboring publication to make it the new centre.