Article
Pediatric Cancer Genetics and Genomics.
Annual review of genomics and human genetics - 1 Aug 2025
Mardis Elaine R
Abstract excerpt
Molecular profiling of DNA and RNA from pediatric cancers by next-generation sequencing has been demonstrated to improve diagnosis and prognosis and to identify somatic alterations indicating vulnerability to targeted therapies. Hence, much like in the treatment of adult cancers, molecular profiling is now routinely utilized in clinical workflows for pediatric cancers as a companion to conventional pathology...
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