Article

Combined landscape of single-nucleotide variants and copy-number alterations in clonal hematopoiesis

2021-03-08

Abstract excerpt

Implicated in the development of hematological malignancies (HM) and cardiovascular mortality, clonal hematopoiesis (CH) in apparently healthy individuals has been investigated by detecting either single-nucleotide variants and indels (SNVs/indels) or copy number alterations (CNAs), but not both. Here by combining targeted sequencing of 23 CH-related genes and array-based CNA detection of blood-derived DNA, we hav...

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Literature Corpus work: 83532c16-9269-5295-b33b-bd87d92da0e5
DOI: 10.1101/2021.03.05.433727

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